1) The lab of Xabier Aranguren, Regenerative Medicine Unit, CIMA University of Navarra, is seeking a highly motivated postdoc candidate to work on a research project focused on the molecular and epigenetic bases of human naïve iPS cells chimeric potential. Revealing cell populations catching the early stages of the human embryo development in naïve pluripotent stem cells. bioRxiv 2022.03.06.482812;doi: https://doi.org/10.1101/2022.03.06.482812Contact Information• Xabier Aranguren, CIMA-University of Navarra, 31008, Pamplona, Spain• Email: email@example.com•Website: https://cima.cun.es/investigacion/programas-investigacion/programa-investigacion-medicina-regenerativa• Please send your application including a motivation letter, your CV and reference letters from your previous employees.
2) PhD position in Pediatric Cancer Epigenetics, Pediatric Cancer Center Barcelona, Spain The Pediatric Cancer Epigenetics group led by Dr. Alexandra Avgustinova is recruiting one PhD student to investigate the molecular mechanisms underlying epigenomically-driven tumourigenesis, using Malignant Rhabdoid Tumours (MRTs) as a model. MRTs are highly malignant and heterogeneous pediatric cancers with abysmal prognosis (5 year survival < 20%). They are characterized by biallelic inactivation of the SWI/SNF subunit SMARCB1, which at the same time represents their only recurrent mutation, making MRTs the best example of epigenetically-driven tumourigenesis. Our larger mission is to identify new clinical intervention nodes for the treatment of MRTs and hence to improve patient welfare and prognosis. The project is multidisciplinary and will involve the use of cell and molecular biology, CRISPR/Cas9, cytometry, microscopy, (epi)genomics and computational biology techniques.ob information: Expected start date: Autumn 2022 Contract length: 3 years, possibility to extend to 4 years. Application deadline: 20th July 2022 To apply: https://hospitalsantjoandedeu.talentclue.com/en/node/87799497/12623479 Please submit academic transcripts and a cover letter with your application.